II-ISO enkulu ye-flangeizinga laziwa ngokuthi yi-LF, LFB, MF noma ngezinye izikhathi nje i-ISO flange. Njengaku-KF-flanges, ama-flange ahlanganiswe nendandatho ephakathi nendawo ne-elastomeric o-ring. I-clamp eyindilinga eyengeziwe elayishwe entwasahlobo ivame ukusetshenziswa eduze kwama-o-rings anobubanzi obukhulu ukuwavimbela ukuthi angagingqiki eringini emaphakathi ngesikhathi sokunyuswa.

Ama-flange amakhulu e-ISO afika ngezinhlobo ezimbili. Ama-ISO-K (noma i-ISO LF) ama-flange ahlanganiswe nezinsimbi ezinezinzipho eziphindwe kabili, ezibambelela emseleni oyindilinga ohlangothini lweshubhu lwe-flange. Amaflange e-ISO-F (noma i-ISO LFB) anezimbobo zokunamathisela ama-flange amabili ngamabholithi. Amashubhu amabili anamaflange e-ISO-K kanye ne-ISO-F angahlanganiswa ndawonye ngokucindezela uhlangothi lwe-ISO-K ngezinsimbi zozipho olulodwa, ezibe seziboshelwa emigodini eseceleni kwe-ISO-F.

Ama-flange amakhulu e-ISO atholakala ngosayizi ukusuka ku-63 kuya ku-500 mm ububanzi beshubhu lokuzisholo.