TheISO wamkulu flangemuyezo umadziwika kuti LF, LFB, MF kapena nthawi zina basi ISO flange. Monga mu KF-flanges, ma flanges amaphatikizidwa ndi mphete yapakati ndi elastomeric o-ring. Chingwe chozungulira chozungulira chomwe chimakhala ndi masika nthawi zambiri chimagwiritsidwa ntchito mozungulira ma-diameter o-mphete kuti zisasunthike kuchokera ku mphete yapakati panthawi yokwera.

Ma flange akuluakulu a ISO amabwera m'mitundu iwiri. Ma flange a ISO-K (kapena ISO LF) amalumikizidwa ndi zikhadabo ziwiri, zomwe zimamatira panjira yozungulira mbali ya chubu la flange. Ma flanges a ISO-F (kapena ISO LFB) ali ndi mabowo omangira ma flanges awiri ndi mabawuti. Machubu awiri okhala ndi ISO-K ndi ISO-F flanges amatha kulumikizidwa palimodzi pomangirira mbali ya ISO-K ndi zikhadabo zamtundu umodzi, zomwe zimamangidwira kumabowo kumbali ya ISO-F.

Ma flanges akulu a ISO amapezeka kukula kwake kuyambira 63 mpaka 500 mm mwadzina chubu awiri.